In Utero Haematopoietic Stem Cell Transplantation (IUHSCT)
نویسندگان
چکیده
In utero haematopoietic stem cell transplantation (IUHSCT) is a non-myeloablative approach for the prenatal treatment of genetic disorders. However, in target disorders, where there is not a selective advantage for donor cells, a useful donor-cell chimerism has not been achieved. There are three possible barriers to engraftment following IUHSCT: limited space in the fetus due to host-cell competition; the large number of donor cells needed, and the immunological asset of recipient.
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عنوان ژورنال:
دوره 1 شماره
صفحات -
تاریخ انتشار 2009